Government Document

Protocol for a randomised controlled trial evaluating the effectiveness of a CBT‑based smartphone application for improving mental health outcomes in adolescents: The MobiliseMe study

Background Depression is a leading cause of disability in adolescents, however few receive evidence-based treatment. Despite having the potential to overcome barriers to treatment uptake and adherence, there are very few CBT-based smartphone apps for adolescents. To address this gap, we developed ClearlyMe®, a self-guided CBT smartphone app for adolescent depression and anxiety. ClearlyMe® consists […]

Prevention of suicide by clozapine in mental disorders: Systematic review

Background Previous research has investigated the efficacy of clozapine in reducing suicidality in patients with schizophrenia and schizoaffective disorder. We aimed to systematically review published evidence, including studies concerning clozapine administration to treat: (a) refractory suicidality in other mental disorders, including bipolar disorder and borderline and other personality disorders; and (b) refractory cases of non-suicidal […]

Prevalence of suicide attempts and correlates among first‑episode and untreated major depressive disorder patients with comorbid dyslipidemia of different ages of onset in a Chinese Han population: A large cross‑sectional study

Background Patients with dyslipidemia are at increased risk for suicide, especially those with major depressive disorder (MDD). Few studies have investigated the independent effects of suicide attempts on comorbid dyslipidemia in patients with MDD. Moreover, there are no comparisons of differences in factors associated with suicide attempts among patients with MDD with dyslipidemia at different […]

Planning for implementation and sustainability of a community‑based suicide surveillance system in a Native American community

Background Native American youth, primarily living on reservations, suffer the highest burden of suicide of any racial group in the USA. Implementation and sustainability of culturally grounded, evidence-based interventions are needed to address suicide in Native American populations. For nearly 40 years, Montana has ranked at or near the top nationwide for suicide. Fort Peck […]

Pain conditions and suicide attempts in military veterans: A case-control design

Objective Specific pain conditions such as back pain and migraines are associated with increased risk of suicide mortality after accounting for key covariates. The purpose of the current study was to assess the associations of specific pain conditions with suicide attempts. Design Case-control Setting Veterans Health Administration (VHA) Subjects Individuals who utilized VHA services with […]

Non-suicidal self-injury and suicide risk among adult medical inpatients

Background Non-suicidal self-injury (NSSI) is a potent risk factor for suicide among youth. There is limited research, however, on the association between NSSI and suicide risk among adults, particularly among adult medical patients, who are a population at increased risk for suicide. To address this research gap, the current analysis aimed to describe the association […]

Non-suicidal self-injury and emotional burden among university students during the COVID-19 pandemic: Cross-sectional online survey

Owing to restrictions of the COVID-19 pandemic, increased stress is evident in university students with a lifetime history of non-suicidal self-injury (NSSI). Therefore, we examined two groups of university students (n = 174) in an online survey, one that exhibited early NSSI in adolescence (n = 51) and another that exhibited continuous NSSI beyond the age of […]

Mood stabilizers and risk of all-cause, natural, and suicide mortality in bipolar disorder: A nationwide cohort study

Objectives People with bipolar disorder have an elevated risk of mortality. This study evaluated associations between the use of mood stabilizers and the risks of all-cause mortality, suicide, and natural mortality in a national cohort of people with bipolar disorder. Methods In this nationwide cohort study, we used data from January 1, 2000, to December […]

Missed opportunities for suicide prevention in teens with ADHD

Background: Epidemiological evidence links Attention Deficit Hyperactivity Disorder (ADHD) to increased risk of suicide. The research aimed to describe awareness among primary care pediatricians (PCPs) of ADHD as a  risk factor for suicide and PCPs’ practices of suicide risk assessment (SRA) and firearms safety assessment (FSA) in teens with ADHD. Method: An online survey was […]

Methylation in MAD1L1 is associated with the severity of suicide attempt and phenotypes of depression

Depression is a multifactorial disorder representing a significant public health burden. Previous studies have linked multiple single nucleotide polymorphisms with depressive phenotypes and suicidal behavior. MAD1L1 is a mitosis metaphase checkpoint protein that has been linked to depression in GWAS. Using a longitudinal EWAS approach in an adolescent cohort at two time points (n = 216 and n = 154), […]

The Traveller Movement: Policy briefing addressing mental health and suicide among Gypsy, Roma and Traveller communities in England

Office for National Statistics (ONS) data reveal that there were 18,998 suicides in men and women aged between 20 and 64 years between 2011 and 2015, and that suicide is the leading cause of death in England in adults below the age of 50. Mortality data published by the ONS are collected from the information […]

Leveraging contextual relatedness to identify suicide documentation in clinical notes through zero shot learning

Invariance-based causal prediction to identify the direct causes of suicidal behavior

Despite decades of research, the direct causes of suicide remain unknown. Some researchers have proposed that suicide is sufficiently complex that no single variable or set of variables can be determined causal. The invariance-based causal prediction (ICP) is a contemporary data analytic method developed to identify the direct causal relationships, but the method has not […]

Internet searches for “insomnia” and “suicide” mediated by stay-at-home behaviors in 45 countries during the first 12 months of the COVID-19 pandemic

Background This study aimed to investigate (1) the mental health impacts (i.e., insomnia and suicide ideas) of the COVID-19 pandemic and (2) the mediation effects of stay-at-home levels on those impacts. Methods This study investigated monthly national COVID-19 deaths, stay-at-home levels, and internet searches for words for “insomnia” and “suicide” across 45 countries during the […]

Increasing trend in violence-related trauma and suicide attempts among pediatric trauma patients: A 6-year analysis of trauma mechanisms and the effects of the COVID-19 pandemic

Background: Trauma is the leading cause of morbidity and mortality in the pediatric population. During the COVID-19 pandemic (COVID-19), different trends for pediatric trauma (PT) were described. This study aims to explore the trend over time of PT in our center, also considering the effects of COVID-19, focusing on trauma mechanisms, violence-related trauma (VRT) and […]

How people diagnosed with borderline personality disorder experience relationships to oneself and to others: A qualitative in-depth study

Materials and methods Results Discussion Conclusion Acknowledgements Disclosure statement Additional information References   ABSTRACT Background The first-person experiences of people diagnosed with borderline personality disorder (BPD) is an important area of research. It can support clinical and ethical practice, and nuance and expand on insights offered by diagnostic and treatment-oriented research approaches. In this study, […]

Global prevalence of suicide in patients living with HIV/AIDS: A systematic review and meta-analysis

Background In fact, people living with HIV are at a greater risk of mental health disorders. Based on lack of necessary information in this area the present systematic review and meta-analysis study was conducted to determine the magnitude of committed suicides among HIV/AIDS people as well as their associated factors in a global setting. Method […]

Food insufficiency, adverse childhood experiences and mental health: Results of the Singapore Mental Health Study 2016

Objective: This study aimed to investigate the prevalence and correlates of food insufficiency and its association with mental disorders and adverse childhood experiences (ACE) in Singapore. Design: This analysis utilised data from the Singapore Mental Health Study (SMHS 2016). Setting: SMHS 2016 was a population-based, psychiatric epidemiological study conducted among Singapore residents. Participants: Interviews were […]

Evaluation of suicide among Iranian ex-prisoners of war in Iraq detention camps (1980-90)

Background: Prisoners of war (POWs) are usually at risk of suicide due to problems such as torture, social and emotional deprivation, etc. The present study aimed to investigate suicide cases among Iranian prisoners of war (POWs) over ten years of their presence in the camps in Iraq (1980-1990). Methods: Data required in this study were collected in […]

Epidemiology of suicide in the Tri‑City metropolitan area in Poland in 2010–2019

The paper, which is a continuation of our previous epidemiological studies on the phenomenon of suicide in the Tri-City metropolitan area, presents the results of statistical analyses of suicides in the autopsy material of the Department of Forensic Medicine of the Medical University of Gdańsk in the years 2010–2019. The purpose of the study was […]

Engaging stakeholders to develop a suicide prevention learning module for Louisiana firearm training courses

Background: Firearm suicide is a significant public health problem in the United States of America among the general and veteran populations. Broad-based preventive strategies, including lethal means safety, have been emphasized as a key approach to suicide prevention. Prior research has identified ways to improve the reach and uptake of lethal means safety messages. However, few […]

Dysphoria spectrum in the evaluation of suicide risk: An overview and exploratory study

Background: The aim of the present paper was to summarize the role of dysphoria in the development of suicidality. We performed an exploratory study to evaluate dysphoria dimensions in inpatients suffering from  borderline personality disorder (BPD), mood disorders, and schizophrenia spectrum disorders who were evaluated due to suicidal ideation or suicide attempt. Subjects and methods: […]

Depression and suicidality among adolescents living with human immunodeficiency virus in Lagos, Nigeria

Background Nigeria is considered to have the second highest number of people living with human immunodeficiency virus (HIV) worldwide with a national HIV infection prevalence of 5.2% in children and adolescents. Adolescents with HIV-infection have been reported to be more prone to developing comorbid emotional difficulties including depression and suicidality compared to those without HIV-infection. […]