Harm reduction is a critical piece of the continuum of care for those experiencing harms related to substance use. This report is intended for ministers of health, chief public health officers, individuals working in health policy and system planning, and decision makers from municipal to federal levels. It provides them with an understanding of how the overdose emergency combined with the COVID-19 pandemic is affecting those providing response services. This report is also intended for employers, leaders, benefit and employee assistance providers, and governments. For them, this report highlights the actions that need to be taken to ensure appropriate resources are available to support the well-being of harm reduction providers.