Cardiovascular Drugs and the Risk of Suicide: a Nested Case-Control Study

The possible association between the use of cardiovascular drugs & suicide was investigated using population-based register data. A nested case-control study in Funen County, Denmark was performed. 743 suicides were identified for the period 1991-1998 & compared to 14,860 age- & gender-matched controls. Conditional logistic regression was used to analyze the data. The risk of suicide was not associated with current exposure to lipid-lowering drugs, calcium channel blockers, beta-blockers, or angiotensin-converting-enzyme inhibitors. Suicide risk was associated with current angiotensin-receptor antagonist use based on 5 of the cases exposed. (21 refs.)