Serotonin Transporter Distribution and Density in the Cerebral Cortex of Alcoholic and Nonalcoholic Comparison Subjects: a Whole-Hemisphere Autoradiography Study

The aims of this study were to identify putative areas in the human brain that are rich in serotonin transporter sites, particularly within the medial prefrontal cortex, & to determine whether serotonin transporter density in this area is altered among alcoholic subjects. Serotonin transporter density was measured among 17 alcoholic & 10 nonalcoholic comparison subjects by postmortem whole-hemisphere autoradiography with 3Hcitalopram. Data from suicide victims is included. (35 refs)