Year: 1994 Source: BMJ, v.209, (10 December 1994), p.1546-1549 SIEC No: 20040901

The authors sought to identify factors that affect physicians’ choice of specific antidepressant drugs in order to evaluate the validity of epidemiological studies of the risks (particularly suicide) & benefits of different compounds. They found that Amitriptyline was the most common first line drug of choice among both psychiatrists & general practitioners, although low toxicity compounds (mainly lofeparmine, mianserin, & moclobemide) were more often the drug of choice in depression associated with the overt risk of suicide. (15 refs)