Year: 2003 Source: Journal of Nervous and Mental Disease, v.191, no.7, (July 2003), p.444-449 SIEC No: 20040271

The purpose of this study was to examine the extent of suicidal ideation & hopelessness in outpatients with treatment-resistant depression (TRD) & to study the impact of suicidal ideation & hopelessness on treatment with nortriptyline (NT). Using items #3 & #30 of the Hamilton Depression Rating Scale in 89 patients with TRD, & the Beck Hopelessness Index in 40 of these patients, it was found that more than half of patients with prominent hopelessness who completed the trial responded to NT. (39 refs)