Clonazepam as an Augmenting Agent in the Treatment of Childhood-Onset Obsessive-Compulsive Disorder

This case study is of a young man with childhood onset of severe obsessive-compulsive disorder (OCD). The patient had no improvement during trials of clomipramine, fluoxetine, and fluvoxamine. The patient consumed 50 tablets of fluoxetine in a suicide attempt, and experienced a total remission of his OCD sypmtoms for the first time; this lasted approximately 1 month. Subsequently, the patient was able to achieve a 75% improvement, when treated with a combination of fluoxetine, and clonazepam.