Year: 1992 Source: Archives of General Psychiatry, v.49, no.10, (October 1992), p.774-781 SIEC No: 19920906

Cognitive therapy & pharmacotherapy, each singly & in combination, were compared in the treatment of nonpsychotic, nonbipolar depressed outpatients. 66% of patients reported suicidal ideation at intake. 39% had attempted suicide during their lifetime. 2 patients died as a consequence of suicide attempts, both of which involved study medication. Combining cognitive therapy with pharmacotherapy did not markedly improve response over that observed for either modality alone. (30 refs.)