Year: 1992 Source: Journal of Affective Disorders, v.24, no.1, (January 1992), p.1-10 SIEC No: 19920206

An analysis of clinical trial data comparing fluoxetine & placebo was undertaken to assess the potential association of fluoxetine & suicidality in patients with DSM-IIIR obsessive-compulsive disorder. Worsening in suicidal ideation was significantly more frequent with placebo than with fluoxetine. The emergence of substantial suicidal ideation was numerically greater with placebo than with fluoxetine. Thus results suggested no undue risk of suicidality in OCD patients treated with fluoxetine.