2-Year Follow-Up of Subjects and Their Families Defined as at Risk for Psychopathology on the Basis of Platelet MAO Activities

College students hypothesized as being at risk for psychiatric dysfunction solely on the basis of their MAO platelet activities were briefly interviewed 2 years after completion of inital studies. These 33 low-MAO subjects reported more job instability than 30 high-MAO control subjects. Moreover, the low-MAO males had fallen about half a year behind their high-MAO counterparts in school. More low-MAO male subjects reported mental health probelms in their families, esp. depression & suicide.