To assess the frequency of affective disorders among pathological gamblers, 50 patients admitted to the gambling treatment program of a Veterans Administration hospital were tested. 76% of subjects were diagnosed as having major depressive disorder & 38% as having hypomanic disorder. The patients with major depressive disorder & 1 patient with schizoaffective disorder, depressed type, were more likely to miss work because of gambling. A large number of patients displayed suicidal tendencies.