Year: 1984 Source: Canadian Journal of Psychiatry, v.29, no.1, (1984), p.11-13 SIEC No: 19841681

In a matched controlled study 72 Canadian patients with a major depressive episode were compared with non-depressed and never depressed orthopedic patients. Significantly more of the depressives had parental loss before 17 years of age, a poor marriage before the onset of depression and a family history of depression.