Year: 1982 Source: Neuroscience and Behavioral Physiology, v.12, no.2, (1982), p.92-96 SIEC No: 19840395

18 manic-depressives were given antidepressants during sleep deprivation. Results show that improvement was gradual, usually occuring between 9:00 a.m. & 12 noon. Patients showed a reduction in depressive symptoms including a disappearance of suicidal tendencies. 7 subjects were cured while 11 showed a regression to their former state. (MRE)