With but one exception world-wide, males complete suicide at rates exceeding those of females. The male to female suicide ratio in the United States is greater than 4:1. Explanatory hypotheses for these findings focus on gender role behaviors, specifically the greater involvement of men in high-risk health behaviors and the greater propensity of women to seek and use supports for help when in need. This paper explores what is known about gender differences in help-seeking behavior to determine factors that may promote increased help-seeking among men. On the basis of this research, we propose public health intervention approaches that have potential to motivate men at-risk for suicide to seek and receive help.