Older adults and planning for firearm safety: A qualitative study of healthcare providers

Purpose/Background Firearm injury, particularly self-directed, is a major source of preventable morbidity and mortality among older adults. Older adults are at elevated risk of serious illness, cognitive impairment, and depression—all known risk factors for suicide and/or unintentional injury. Healthcare providers are often the first to identify these conditions and, although they commonly deliver safety guidance […]

Argyrophilic grain disease is common in older adults and may be a risk factor for suicide: A study of Japanese forensic autopsy cases

Background Neuropathological diagnosis of argyrophilic grain disease (AGD) is currently based primarily on the combination of argyrophilic grain (AG) visualized using Gallyas–Braak silver staining, phosphorylated tau-positive pretangles, coiled bodies, and ballooned neuron detection. Although AGD is common in patients with dementia and/or prominent psychiatric symptoms, whether it is a distinct neurological disease entity or a […]

Long-term exposure to air pollution and mortality from dementia, psychiatric disorders, and suicide in a large pooled European cohort: ELAPSE study

Ambient air pollution is an established risk factor for premature mortality from chronic cardiovascular, respiratory and metabolic diseases, while evidence on neurodegenerative diseases and psychiatric disorders remains limited. We examined the association between long-term exposure to air pollution and mortality from dementia, psychiatric disorders, and suicide in seven European cohorts. Within the multicenter project ‘Effects […]

Association of 5α-reductase inhibitors with dementia, depression, and suicide

Importance  In recent decades, there has been increased interest in the possible adverse neurological effects of 5α-reductase inhibitors (5-ARIs), which have been used mainly for benign prostatic hyperplasia and androgenic alopecia. Numerous studies and reports have indicated associations of 5-ARIs with depression and suicide. However, most of these studies had methodological shortcomings, and very little is […]

Risk of suicide after dementia diagnosis

Importance  Patients with dementia may be at an increased suicide risk. Identifying groups at greatest risk of suicide would support targeted risk reduction efforts by clinical dementia services. Objectives  To examine the association between a dementia diagnosis and suicide risk in the general population and to identify high-risk subgroups. Design, Setting, and Participants  This was a population-based case-control […]

Risk of suicide after dementia diagnosis

Objectives  To examine the association between a dementia diagnosis and suicide risk in the general population and to identify high-risk subgroups. Design, Setting, and Participants  This was a population-based case-control study in England conducted from January 1, 2001, through December 31, 2019. Data were obtained from multiple linked electronic records from primary care, secondary care, and the […]

Understanding suicide risk in people with dementia and family caregivers in South Korea: A systematic review

Dementia-related suicide is not well known. This study aimed to understand the characteristics of suicide risk among people with dementia and dementia family caregivers in South Korea. According to a systematic review of PRISMA guidelines, six electronic databases were searched for research published from 2010 to 2021. Ten studies were included. Among the included studies […]

Risk of suicide attempt in patients with recent diagnosis of mild cognitive impairment or dementia

Objectives  To examine the association between diagnoses of MCI and dementia and suicide attempt and explore potential psychiatric moderators and to assess whether the association differs based on recency of diagnosis. Design, Setting, and Participants  This nationwide cohort study integrated 5 national databases from the Department of Veterans Affairs (VA) and Centers for Medicare & Medicaid Services […]

Risk of suicide attempt in patients with recent diagnosis of mild cognitive impairment or dementia

Importance  Little is known about the association between mild cognitive impairment (MCI) and suicide. Most studies have focused on dementia and suicidal behavior, with inconsistent results. Objectives  To examine the association between diagnoses of MCI and dementia and suicide attempt and explore potential psychiatric moderators and to assess whether the association differs based on recency of diagnosis. […]

A comprehensive review of computer-aided diagnosis of major mental and neurological disorders and suicide: A biostatistical perspective on data mining

The World Health Organization (WHO) suggests that mental disorders, neurological disorders, and suicide are growing causes of morbidity. Depressive disorders, schizophrenia, bipolar disorder, Alzheimer’s disease, and other dementias account for 1.84%, 0.60%, 0.33%, and 1.00% of total Disability Adjusted Life Years (DALYs). Furthermore, suicide, the 15th leading cause of death worldwide, could be linked to […]

Predictors of suicide in patients with dementia

Background Assessing predictors of suicide and means of completion in patients with dementia may aid the development of interventions to reduce risk of suicide among the growing population of individuals with dementia. Methods This national, retrospective, cohort study used data from the Department of Veterans Affairs (fiscal years 2001–2005). The sample included patients ≥60 years […]

A complex relationship between suicide, dementia, and amyloid: A narrative review

Background: Suicide rates are high among older adults and many conditions have been related to suicide in this population: chronic illnesses, physical disabilities, cancer, social isolation, mental disorders and neurocognitive disorders. Objectives: Among neurocognitive disorders, analysis of the relationships between dementia and suicidal behaviors led to conflicting results and some questions are still without answer. […]

Suicidal ideation and behavior assessment in dementia studies: An internet survey

Introduction The AARR task force on suicidal ideation and behavior (SI/SB) in dementia conducted an online survey on the extent of SI/SB in individuals diagnosed with mild cognitive impairment (MCI) or dementia who were participating in clinical trials. Methods Investigators with experience in conducting SI/SB assessments in clinical trial subjects with MCI or dementia were […]

Acute risk of suicide and suicide attempts associated with recent diagnosis of mental disorders: A population-based, propensity score-matched analysis.

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Suicidal ideation in family carers of people with dementia: A pilot study.

The objective of this pilot study was to gather preliminary evidence on suicidal ideation in family carers of people with dementia. An online, cross-sectional survey was conducted with 120 family carers, the majority of whom were located in Australia and USA. The survey included measures of suicidality, self-efficacy, physical health, depression, hopelessness, anxiety, optimism, caregiver […]