Association between cannabis use disorder and self- and other-directed aggression

Cannabis is the most widely used drug worldwide. Data about the association of cannabis use with aggression is heterogeneous. The objective of the current study was to assess the nature of the association between cannabis use disorder (CUD) and self-directed, other-directed, and combined aggression. We used data from the National Survey on Drug Use and […]

Marijuana use is associated with suicidal ideation and behavior among US adolescents at rates similar to tobacco and alcohol

This study used data from the National Youth Risk Behavior Survey to examine the association between adolescent marijuana, tobacco, and alcohol use and suicidal ideation and attempts over a period of six years (2011–2017), as attitudes and laws became more permissive of marijuana use. We used logistic regression to control for possible confounders, estimate marginal […]

Suicidal ideation, planning, and attempts among synthetic cannabinoid users across different demographic subgroups

Case studies have linked synthetic cannabinoid (SC) use to suicide risk both during and following acute psychoactive effects. No study has explored whether a meaningful relationship exists between SC use and suicidal ideation, planning, and attempts within a generalizable sample. Aims: This work attempted to determine whether SC use is significantly associated with suicidal thoughts, planning, or […]

Associations of suicidality trends with cannabis use as a function of sex and depression status

Objective  To determine whether cannabis use and cannabis use disorder (CUD) are associated with a higher prevalence of suicidality among young adults with or without depression and to assess whether these associations vary by sex. Design, Setting, and Participants  This survey study examined data from 281 650 adults aged 18 to 34 years who participated in the National […]

Evaluation of state cannabis laws and rates of self-harm and assault

Objective: To evaluate the association of state medical and recreational cannabis laws with self-harm and assault, overall and by age and sex, while considering varying degrees of commercialization. Design, setting, and participants: Using a cohort design with panel fixed-effects analysis, within-state changes in claims for self-harm and assault injuries before and after changes in cannabis laws were […]

A genetically informed study on the association of cannabis, alcohol, and tobacco smoking with suicide attempt

Use of substances such as cannabis, alcohol, and tobacco, has been associated with increased risk of suicide attempt in several observational studies. However, establishing whether these associations are causal is challenging when using observational designs. To evaluate the potential causal contributions of cannabis use, alcohol use, and tobacco smoking to suicide attempt, we applied two-sample […]

Shaping future investments in community-based research on cannabis and mental health: A community-based research forum [Summary report]

The Shaping Future Investments in Community-Based Research on Cannabis and Mental Health forum relied on the expertise of people with lived experience of substance use and/or mental health problems and illnesses, family members, caregivers, policy makers, and community-based researchers to discuss appropriate approaches to and topics for community-based research. The event had four main goals: […]

Does cannabis use modify the effect of post-traumatic stress disorder on severe depression and suicidal ideation? Evidence from a population-based cross-sectional study of Canadians

BACKGROUND: Post-traumatic stress disorder sharply increases the risk of depression and suicide. Individuals living with post-traumatic stress disorder frequently use cannabis to treat associated symptoms. We sought to investigate whether cannabis use modifies the association between post-traumatic stress disorder and experiencing a major depressive episode or suicidal ideation. METHODS: We used data from the 2012 […]

The relationship between cannabis involvement and suicidal thoughts and behaviors

BACKGROUND: In the present study, we examined the relationship between cannabis involvement and suicidal ideation (SI), plan and attempt, differentiating the latter into planned and unplanned attempt, taking into account other substance involvement and psychopathology. METHODS: We used two community-based twin samples from the Australian Twin Registry, including 9583 individuals (58.5% female, aged between 27 […]

Cannabis use disorder and post-deployment suicide attempts in Iraq/Afghanistan-era veterans

The objective of the present study was to use retrospective data to test the hypothesis that cannabis dependence would be associated with an increased rate of post-deployment suicide attempts. Participants included 319 veterans who had deployed to either Iraq or Afghanistan. Study procedures involved completion of a structured clinical interview and a battery of self-report […]

Relationship between suicide attempts and synthetic cannabinoids in adjustment disorder

Objective: Although it has been known that adult patients with an adjustment disorder diagnosis do not have suicidal behavior similar to adolescents, the validity of this assertion in particular groups is unknown. This study was designed to determine the prevalence and risk factors associated with suicide in patients with adjustment disorder that resulted in suicide […]

Major depressive disorder, suicidal thoughts and behaviours, and cannabis involvement in discordant twins: A retrospective cohort study.

Early and frequent cannabis use are associated with an increased likelihood of major depressive disorder (MDD) as well as suicidal thoughts and behaviours. We identify associations between aspects of cannabis use, MDD, and suicidal thoughts and behaviours and examine whether such associations persist after accounting for those predisposing factors, including genetic liability and early family environment, that are shared […]

Cannabis involvement and nonsuicidal self-injury: A discordant twin approach.

Cannabis use, particularly at an early age, has been linked to suicidal thoughts and behavior, but minimal work has examined the association between cannabis use and lifetime nonsuicidal self-injury (NSSI). The current study aims to characterize the overlap between lifetime and early cannabis use and NSSI and to examine genetic and environmental mechanisms of this […]