Abstract
Depressed suicide attempters have smaller hippocampus than depressed patients without suicide attempts.
Colle, R.~~Chupin, M.~~et al.
Hippocampal volumes were assessed with automatic segmentation in 63 depressed patients with or without suicide attempts. Suicide attempters had lower total hippocampus volumes than non-attempters, especially for acute suicide attempts. These differences were independent from socio-demographics and major depressive disorder characteristics. A total hippocampal volume threshold of 5.00 cm3 had a 98.2% negative predictive value for acute suicide attempts. Hippocampal volume could be a suicidal state marker in major depressive episodes.
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