Suicide Risk in men With Prostate-Specific Antigen-Detected Early Prostate Cancer: a Nationwide Population-Based Cohort Study from PCBaSe Sweden

This study assessed the risk of suicide among men diagnosed with prostate cancer subsequent to prostate-specific antigen testing. The number of suicides registered for cases in the PCBaSe cohort was compared with the expected number of suicides in an age-matched general male Swedish population. Standardised mortality ratios were calculated for different categories of cases. There were 128 suicides among the 77,439 prostate cancer cases in the registry compared with an expected number of 85. No increased risk of dying by suicide was observed among men with prostate cancer diagnosis subsequent to prostate-specific antigen testing, whereas the risk was twice as high among men with locally advanced or metastatic disease, compared with an age-matched male population. (25 refs.) JA

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