The study was conducted to identify risk factors associated with parasuicide in a state prison setting that might provide direction and focus for prevention. A proposed model tested the ability of current clinical and background variables to predict parasuicide during incarceration among male inmates. Psychiatric history, symptomatology, and psychological functioning variables affected parasuicide directly and indirectly through their contribution to suicidal ideation. Among inmates with histories of alcohol abuse, however, hopelessness was a less significant predictor of parasuicide, suggesting that interaction effects may warrant more attention.