In this article, the author highlights the Reconnecting Youth (RY) Prevention Research Program. After clarifying the meaning of indicated prevention, she reviews what was learned from 1) descriptive studies of adolescents; 2) screening, instrumentation, & recruitment studies; 3) creating preventive interventions; & 4) experimental studies of various RY prevention approaches. She concludes with the impact of this program of research & anticipated future directions. (60 refs)