Abstract
Emergence of Self-Destructive Phenomena in Children and Adolescents During Fluoxetine Treatment
King R A~~Riddle M A~~et al
This study analyzed the effect of fluoxetine treatment for obsessive-compulsive disorder among 6 patients, 10 to 17 years old. The authors found that self-injurious ideation or behavior appeared or intensified during the treatment. 3 hypotheses are discussed: coincidence; medication-induced agitation, disorganization, or mood changes; or, a specific serotonergic-mediated effect on the regulation of aggression. (VM)