Resource Tag: ANALGESICS

Background: Analgesics prescriptions may provide a marker for identifying individuals at higher risk of suicide. In particular, awareness of which analgesics are implicated may help clinicians assess and modify risk. Method: A case–control study in England using the Clinical Practice Research Datalink (for primary care records) linked with hospital and national mortality electronic registries. We […]

In the U.S., intentional self-poisonings with analgesics that are available without a prescription increased from 2000 to 2018. Given concerns regarding mental health outcomes during the COVID-19 pandemic, we examined and compared trends in pediatric and adult intentional self-poisoning with acetaminophen, aspirin, ibuprofen, and naproxen from 2016 to 2021 using the National Poison Data System […]

Purpose The present study examined associations between nonmedical use of prescription opioids and serious psychological distress, suicidal ideation, and suicide attempts, and tested whether age and sex moderate these relationships. Methods Data on 5582 adolescents were obtained from a representative province-wide survey of students in grades 7 through 12 (mean age: 15.3 years) across Ontario, Canada. […]

Post-treatment Lyme disease syndrome (PTLDS) is a pain disorder for which there remains no gold standard treatment option. Here, we report a case of PTLDS in a female patient whose pain was refractory to treatment options such as radiofrequency ablation, vitamin infusion therapy, opioid analgesics, and other pharmacotherapies. The patient commenced an experimental intravenous ketamine […]

The goal of this study was to examine the relationship between past-year frequency of prescription opioid misuse and past-year suicidal ideation, suicide planning, and suicide attempts. Secondary data analyses were conducted using data from 41,053 participants of the 2014 National Survey of Drug Use and Health. Past-year frequency of prescription opioid misuse was grouped into […]

This study examined what effect the withdrawal of co-proxamol from the United Kingdom market had on mortality from poisoning in Scotland. A retrospective, observational study of mortality due to poisoning by single agents was done for the period 2000-2006. A significant reduction in the proportion of poisoning deaths due to co-proxamol was observed following legislation. […]

In this letter to the editor, the authors discuss children & adolescents who were admitted to the Teaching Hospital in Karapitiya (Sri Lanks) following deliberate self-harm. Admissions for deliberate self-harm increased by 91% from 2001 to 2007 with girls accounting for most of this increase. Admissions for deliberate self-harm increased consistently with age. Admissions after […]

This study described substances used in overdose & the characteristics of patients admitted with medicinal drug overdose in an urban tertiary care hospital in Colombo. A descriptive study of 191 patients admitted with intentional self-poisoning was carried out. Medicinal drugs were the most common substance used in overdose. Those who used medicinal drugs were mainly […]

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This study assessed the effect of the UK Committee on Safety of Medicines’ announcement in January 2005 of withdrawal of co-proxamol on analgesic prescribing & poisoning mortality. An interrupted time series analysis for 1998-2007 was done. A steep reduction in prescribing of co-proxamol occurred in the post-intervention period, 2005-2007, such that the number of prescriptions […]

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Inquest records in 24 coroners’ jurisdictions in England on deaths between 2000-2001 which received a verdict of etiher suicide or undetermined cause (with a high or moderate probability of suicide) were examined. 123 coproxamol poisoning suicides were identified. Alcohol was involved in 58.5% of cases. Younger people were more likely to have consumed alcohol & […]

Objective To describe how changes in legislation to control sales and thus restrict the general availability of paracetamol have affected deprivation-related inequalities in deliberate self-harm associated with the drug in Scotland. Design and setting A descriptive analysis of routine death and hospital discharge data for the entire Scottish population between 1995 and 2002. Participants Patients […]

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Refer to SIEC # 2007-0661 for the article by Morgan et al

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For the original study, please see SIEC #2003-0341

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