Posttraumatic stress disorder (PTSD) is a disabling psychiatric disorder common among military personnel and veterans. First-line psychotherapies most often recommended for PTSD consist mainly of Òtrauma-focusedÓ psychotherapies that involve focusing on details of the trauma or associated cognitive and emotional effects. In military and veteran populations, trials of the first-line trauma-focused interventions cognitive processing therapy and prolonged exposure have shown clinically meaningful improvements for many patients with PTSD. However, nonresponse rates have been high, many patients continue to have symptoms, and trauma-focused interventions show marginally superior results compared with active control conditions. There is a need for improvement in existing PTSD treatments and for development and testing of novel evidence-based treatments, both trauma-focused and nonÐtrauma-focused.
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