Year: 2015 Source: Journal of Psychiatric Research.(2015).61:13Ð18.doi:10.1016/j.jpsychires.2014.12.010 SIEC No: 20150098

Hippocampal volumes were assessed with automatic segmentation in 63 depressed patients with or without suicide attempts. Suicide attempters had lower total hippocampus volumes than non-attempters, especially for acute suicide attempts. These differences were independent from socio-demographics and major depressive disorder characteristics. A total hippocampal volume threshold of 5.00 cm3 had a 98.2% negative predictive value for acute suicide attempts. Hippocampal volume could be a suicidal state marker in major depressive episodes.

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