Functional MRI of pain application in youth who engaged in repetitive non-suicidal self-injury vs. psychiatric controls.

Year: 2014 Source: Psychiatry Research: Neuroimaging.(2014).223(2):104Ð112. DOI: 10.1016/j.pscychresns.2014.05.003 SIEC No: 20140261

Highligthts Brains of young adult patients who engage in NSSI differed from non-NSSI patients in reward-processing areas. These differences were evident when patients self-administered a painful stimulus in the scanner. ÒReliefÓ correlated with BOLD signal in thalamus and striatumÐareas implicated in pain and reward-processing. Connectivity between OFC and ACC was diminished in NSSI patients compared with psychiatric controls.

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Osuch, E.Ford, K.et al.