The Methamphetamine Treatment Project offers the opportunity to examine co-occurring psychiatric conditions in a sample of 1016 methamphetamine users participating in a multisite outpatient treatment study between 1999-2001. Participants reported high levels of psychiatric symptoms, particularly depression & attempted suicide, but also anxiety & psychotic symptoms. Overall, 27% of the sample reported a lifetime suicide attempt. 13% of males reported a lifetime suicide attempt compared to 28% of females. Findings continue to support the value of integrated treatment for co-occurring conditions, especially the importance of training counselling staff to handle psychotic symptoms when needed. (32 refs)