In this letter to the editor, Isacsson comments on a previous study by Reseland et al (2006) on suicide & the use of antidepressants in the four Nordic countries. Isacssson notes the classification of deaths was changed in 1969 with the introduction of the category of uncertain cause of death in ICD-8 &, therefore, some of the findings in the Reseland et al study may be artefacts. The reply of Reseland et al follows.