With a distinction between individual & collective experiences with discrimination, the authors used path analysis to test previous assertions that African American distrust of medicine leads to more negative attitudes toward euthanasia. Results indicate that while African Americans exhibit higher levels of distrust of medicine, this is not related to attitudes toward euthanasia, which seem predominantly to be a spiritual matter. Results from this study have implications for legislative policy, treatment interventions, doctor-patient relations, & sociological understanding of the interaction of race, spirituality, experience, & attitudes. (32 refs.)