Year: 2006 Source: Current Drug Safety, v.1, no.1, (January 2006), p.59-62 SIEC No: 20060960

This article raises & discusses issues related to the use of selective serotonin reputake inhibitors with children & adolescents. The issues are whether there is an overuse of antidepressants & does the risk of suicide increase with the prescription of antidepressants in the whole population. Is the response to antidepressants modified during adolescence &, if so, by what mechanisms? The current criteria for defining the depressive state are still similar to those employed in the 19th century; it is concluded, therefore, that there is a need to develop an evidence-based approach to psychiatry that aims to delineate diagnostic categories predictive of the response to treatment. (37 refs.)