Year: 2002 Source: Arquivos de Neuro-Psiquiatria, v.60, no.3-b, (September 2005), p.721-724 SIEC No: 20051776

The authors report a case of depression & suicide ideation that began with the start of increased doses of interferon beta-1a & their complete reversal following the drug withdrawal. The patient was a 21-year-old male with multiple sclerosis & no past history of affective disorders. This case suggests patients with multiple sclerosis may develop depression & suicidal thoughts when treated with hgh doses of interferon beta-1a. (35 refs.)