Is Suicide Ideation a Surrogate Endpoint for Geriatric Suicide?
Links P S~~Heisel M J~~Quastel A
The present study explored the validity of treating suicide ideation as a surrogate endpoint that can serve as a proxy for suicide in clinical intervention research with suicidal seniors. 2 criteria, that suicide ideation is modulated by the proposed intervention & that modulation of suicide ideation leads to a quantitative reduction in suicide rates, were the focus of this review. Analyses provided modest evidence for suicide ideation as a surrogate endpoint for geriatric suicide. Implications of using surrogate endpoints in suicide research are discussed. (71 refs)