Abstract
Impaired Repression at a 5-Hydroxytryptamine 1A Receptor Gene Polymorphism Associated With Major Depression and Suicide
Lemonde S~~Turecki G~~et al
Inhibition of serotonergic raphe neurons is mediated by somatodendritic 5-HT1A autoreceptors, which may be increased in depressed patients. The authors report an association of the C(-1019)G 5-HT1A promoter polymorphism with major depression & suicide in separate cohorts. (64 refs)