Suicide Attempts in Patients With Bipolar I Disorder During Acute and Maintenance Phases of Intensive Treatment With Pharmacotherapy and Adjunctive Psychotherapy

Lifetime rates of suicide attempts among patients with bipolar I disorder were compared to rates during a 2-year period of intensive treatment with pharmacotherapy and with one of two adjunctive psychosocial interventions. The authors found that during treatment the patients experienced a significant reduction in suicidal behaviour. No patient with one or more suicide attempts before entering the trial attempted suicide during the protocol. (19 refs)