Protein Kinase A in Postmortem Brain of Depressed Suicide Victims: Altered Expression of Specific Regulatory and Catalytic Subunits

This study examined the molecular basis of reduced 3Hcyclic adenosine monophosphate binding & catalytic activity of protein kinase A in prefrontal cortex of depressed suicide victims, & whether these findings could be replicated in another cohort. (47 refs)