Year: 2003 Source: Neuropsychopharmacology, v.28, no.1, (January 2003), p.163-169 SIEC No: 20030703

This study was performed in order to test the potential genetic relationships between the 5-HT(1B) receptor & several psychopathologies including pathological aggression, alcoholism & suicide. The findings indicate that substance abuse disorder & major depression are associated with the 5-HT(1B) G861C locus in the patient population, but other psychopathologies such as bipolar disorder, schizophrenia, alcoholism, & suicide attempts were not found to be associated with this polymorphism. (39 refs)