Interferon Treatment is not Associated With a Worsening of Psychiatric Symptoms in Patients With Hepatitis C

This study prospectively examined the psychiatrist side effects of interferon in patients with hepatitis C. 63 consecutive patients at a New Zealand hepatitis clinic were interviewed & completed a psychiatric symptom questionnaire. Results indicate that patients on interferon did not suffer a drop in mood. The subgroup with past depression also did not suffer an increase in depressive symptoms. No patients attempted suicide. The authors conclude withholding interferon treatment because of the possibility of worsening psychiatric symptoms is unwarranted. (13 refs) (SC)