Reports a case of toxic ingestion of cyproheptadine in a suicide attempt in a 15-yr-old adolescent female. The patient had a history of steroid-dependent, frequently relapsing, minimal-change nephrotic syndrome & atopic dermatitis, for which she had been treated with cyproheptadine. Following diagnosis with cyproheptadine poisoning, the patient was given activated charcoal & magnesium sulfate via a tube. Phenobarbital & diazepam were given for agitation & confusion. She was released on the 10th day of her hospital stay with psychiatric follow-up. The authors cite other cases of suicide attempts with cyproheptadine, & the need for medical staff & parents to take care in its management. (5 refs)