Electroconvulsive Therapy in Medication-Nonresponsive Patients With Mixed Mania and Bipolar Depression

The aim of this study was to investigate the effectiveness of electroconvulsive therapy (ECT) in medication-nonresponsive patients with mixed mania & bipolar depression. In our study, the ECT was associated with a substantial reduction in symptomatology, in both patients with mixed mania & those with bipolar depression. However, the mixed mania group exhibited a more rapid & marked response as well as a greater reduction in suicidal ideation. Response to ECT was not influenced by the presence of delusions. (30 refs)