Year: 2001 Source: American Journal of Psychiatry, v.158, no.8, (August 2001), p.1271-1275 SIEC No: 20011616

The purpose of this study was to determine if fear of an increased risk of attempted suicide in placebo groups participating in placebo-controlled studies is an argument against the performance of placebo-controlled trials in studies of major depression. Based on their findings, the authors conclude that fear of increased risk of attempted suicide in the placebo groups should not be an argument against performing short-term & long-term placebo-controlled trials in major depression. (21 refs)