Abstract
Attempted Suicide and Polymorphism of the Serotonin Transporter Gene in Chinese Patients With Schizophrenia
Chong S~~Lee W~~et al
The association of suicidal behaviour in Chinese patients with schizophrenia with a functional polymorphism of the promoter region of the 5-HTT gene (5-HTTLPR) was examined. The 5-HTTLPR genotype was determined by polymerase chain reaction for 76 suicidal & 262 nonsuicidal patients with a diagnosis of schizophrenia. There was no significant genotypic or allelic association of the 5-HTTLPR polymorphism with a history of attempted sucide. From the results of this study, this 5-HTTLPR polymorphism is unlikely to have a major effect on suicidal behaviour in Chinese patients with schizophrenia. (27 refs.)