Year: 2000 Source: Journal of Clinical Psychiatry, v.61, suppl.3, (2000), p.4-9 SIEC No: 20000016

Literature on the efficacy of clozapine, resperidone, olanzapine, quetiapine, & ziprasidone in the treatment of depression, hostility & suicidality in patients with schizophrenia was reviewed. The studies suggest that atypical antipsychotics may exert therapeutic effects on depression & hostility as well as psychosis. Clozapine & olanzapine may reduce suicidality. These therapeutic actions appear to represent additional advantages of atyptical antipsychotics compared with standard agents.