CSF Monoamine Metabolites in Relation to the Diagnostic Interview for Borderline Patients (DIB)

In the 202 patients studied, patients with borderline personality disorder, did not differ significantly from non borderline personality disorder subjects. However, for the impulse action pattern, the subjects with an intermediate value in the evaluation, had significantly higher levels of 5=HIAA and HVA, suggesting that such higher than normal concentrations may be protective against impulsive or suicidal behavior generated by an underlying psychiatric morbidity due to other risk factors.