Abstract
A Tryptophan Hydroxylase Gene Marker for Suicidality and Alcoholism
Nielsen D A~~Virkkunen M~~et al
Association & sib-pair linkage analyses of a polymorphism in intron 7 of the trytophan hydroxylase gene with suicidality, alcoholism & the Karolinska Scales of Personality were conducted in 804 Finnish alcoholic offenders, controls & their relatives, in a sample that included 369 sib pairs. The intron 7 variant showed significant evidence for linkage to suiciality, severe suicide attempts, alcoholism, & Karolinska Scales of Personality socialization score. (67 refs.)