Year: 1997 Source: New York, NY: The Guilford Press, 1997. p.237-250 SIEC No: 19980562

The neurotransmitter serotonin (5-HT) has increasingly been found to be altered in the brain of suicide victims. This chapter reviews most of the research reports on 5-HT among suicides versus controls & concludes that suicides have: 1) more postsynaptic 5-HT receptors; 2) reduced serotonergic innervation; 3) more & greater density of 5-HT-synthesizing neurons, & 4) morphological alterations in dorsal raphe nucleus (DRN) serotonergic neurons. (67 refs.)