Year: 1997 Source: The Psychiatric Clinics of North America, v.20, no.3, (September 1997), p.563-579 SIEC No: 19980520

This article reviews the research data regarding human neuroendocrine systems & suicidal behaviour. Special emphasis is placed on pharmacochallenge studies. Such studies uniquely allow for functional assessment of neuroendocrine parameters in living subjects. Serotonergic mechanisms have been the most fruitful areas of research. While discussing the major areas of controversy, theoretical approaches to integration are offered. (90 refs.)