Year: 1997 Source: Annals of the New York Academy of Sciences, v.836, (December 29, 1997), p.339-351 SIEC No: 19980450

In this article, the effects of lithium treatment in reducing antisuicidal behavior is reviewed. Of the 28 studies reviewed, patients taking lithium had 8.6 times fewer suicide attempts. In a study of bipolar disordered patients, suicides/suicide attempts were reduced 5.6-fold but after patients discontinued using lithium, suicidal acts rose 7-fold and fatalities increased 9-fold. Thus, there is strong evidence for lithium’s effectiveness in reducing suicidal activity. (56 refs.)