Altered Serotonin Function in Suicide: Evidence From Platelet and Neuroendocrine Studies (IN: The Neurobiology of Suicide: From the Bench to the Clinic, edited by D M Stoff & J J Mann)

Year: 1997 Source: Annals of the New York Academy of Sciences, v.836, (December 29, 1997), p.182-200 SIEC No: 19980441

This paper refers to many other studies that attempt to implicate low levels of 5-HT and 5-HIAA with suicide. However, while a relationship between these 2 chemcicals has been linked with depression, results of 5-HT uptake have been inconsistent with suicide. In this study, researchers decided to measure platelet 5-HT(2A) receptors and found this increased in suicidal patients. Fenfluramine and its effect on prolactin and 5-HT release is also discussed. (59 refs.)

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Pandey G N