Year: 1997 Source: Annals of the New York Academy of Sciences, v.836, (December 29, 1997), p.81-105 SIEC No: 19980437

The relationship between impulsivity & serotonin was studied by comparing “knockout” mice (mice that lacked the 5-HT(1B) receptor) with a control group. Impulsivity was studied because it underlies many social problems including suicide. The study found that knockout mice showed more impulsive aggression & acquired addictions. However, this was not as a result of changes in cognitive functions, as they could still discriminate between immediate small, & delayed large rewards. (95 refs.)