Year: 1998 Source: Journal of Affective Disorders, v.47, no.1-3, (January 1998), p.105-112 SIEC No: 19980291

Using desmethylimipramine defined & Na+ dependent 3H imipramine binding, both 5-HT uptake sites & sites unrelated to 5-HT uptake were examined in frontal cortex, putamen & substantia nigra of suicides with a firm retrospective diagnosis of depression & matched controls. No differences were seen between antidepressant-free suicides & controls, although 3H imipramine binding sites were significantly lower in putamen of non-violent suicides.