Adverse Behavioral Events Reported in Patients Taking Alprazolam and Other Benzodiazepines

A review of the published case reports of adverse behavioral episodes or unexpected psychopathology in patients taking benzodiazephrines was undertaken to determine if these adverse events are more likely to occur with alprazolam, when compared with other currently marketed benzodiazepines. It appears, that some differences between alprazolam and older benzodiazepines, may exist. The older benzodiazepines are more commonly reported to have adverse events than alprazolam.